Comparison of polyclonal antibody sera for early prophylaxis following cardiac transplantation
نویسندگان
چکیده
منابع مشابه
Comparison of polyclonal antibody sera for early prophylaxis following cardiac transplantation.
In order to test different polyclonal antibody regimes as early prophylaxis against cardiac rejection, 42 patients (ages 30 to 60 years) transplanted at the University of Michigan from December 1986 to August 1988 were randomized to receive antithymocyte globulin (ATGAM, Upjohn, n = 19) or antilymphoblast globulin (MALG, University of Minnesota, n = 23). Cyclosporine (CYA), steroids, and azathi...
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Collective pediatric data suggest that anti-T-cell induction therapy with polyclonal antibodies improves the outcome of both short- and long-term renal allograft survival. Polyclonal agents, including thymoglobulin (Thy), a rabbit anti-thymocyte globulin; Minnesota (horse) anti-lymphoblast globulin (ALG); and ATGAM, a horse anti-thymocyte globulin (ATG), all suppress B and T cells. While no spe...
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Serum characterization and antibody isolation are transforming our understanding of the humoral immune response to viral infection. Here, we show that epitope specificities of HIV-1-neutralizing antibodies in serum can be elucidated from the serum pattern of neutralization against a diverse panel of HIV-1 isolates. We determined "neutralization fingerprints" for 30 neutralizing antibodies on a ...
متن کاملMalignant neoplasms following cardiac transplantation.
OBJECTIVE Malignancies have long been recognized as a complication of long lasting immunosuppressive therapy. We reviewed our experience to investigate the incidence and the spectrum of non cutaneous de novo malignant neoplasms. METHODS Between March 1987 and March 1996, 296 patients underwent 303 cardiac transplantation in our service. The population at risk consists of all patients survivin...
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Nine patients have undergone cardiac transplantation at Stanford University Hospital. Three of these showed no clinical evidence of rejection and had essentially normal physical and phonocardiographic findings. There were eight distinct early rejection episodes in the other six patients. Early rejection was accompanied by decreasing QRS voltage, an early diastolic gallop, and frequently a right...
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ژورنال
عنوان ژورنال: Journal of Surgical Research
سال: 1989
ISSN: 0022-4804
DOI: 10.1016/0022-4804(89)90137-6